Opening in April 2021, Cat Cafe Sakura 2号店 marks the chain's expansion into specializing in feline immunodeficiency virus (FIV) positive cats. Also operated by Inagaki Animal Hospital, the 2号店 deliberately focuses on educating visitors about FIV-carrier cats—felines infected with the virus that show no current symptoms and live completely normal lifespans when properly cared for. Despite stigma surrounding FIV status, these cats make wonderful, healthy companions; the 2号店 works to dispel misconceptions and increase adoption prospects for this overlooked population. Creating a home-like sanctuary rather than a conventional cafe experience, the shop emphasizes relaxation and quiet bonding over bustling energy. Since opening, 57 cats have found permanent homes from this location, with the cafe's gentle approach proving that FIV-positive cats deserve the same love and companionship as any other rescue animal.
The 13 FIV-carrier cats at Sakura 2号店 are notably more socialized and human-friendly than typical rescue populations, responding readily to petting and interaction from visitors. Reviewers frequently highlighted the cats' calm, gentle demeanor and receptiveness to affection—describing a peaceful, healing space where even shy visitors could relax and connect. The cats' glossy coats and healthy appearance attest to dedicated staff care and proper nutrition, addressing common concerns about FIV-positive feline health. Unlike more stimulation-focused cafes, the 2号店 cultivates a slower pace ideal for those seeking therapeutic healing; naps during quiet afternoon hours are common, and the cats seem deeply content in their environment. Staff provide thorough explanations about FIV transmission, care requirements, and adoption processes, ensuring visitors leave educated about these special cats' needs and capabilities. The clean, well-maintained space includes Diaino air purification and a dedicated ventilation system, meeting strict infection-control standards.
Cat Cafe Sakura 2号店 operates daily 12:00-19:00 (last entry 18:30), requiring no reservations except during special events. Admission costs ¥1,100/hour for adults, ¥550 for ages 3-middle school, seniors, and disability pass holders (2 and under free). Weekday free-time visits allow stays of any length for ¥1,100 with capacity up to 10 people—significantly more flexible than the 1号店. Bottled drinks sell for ¥150; treats and toys cost ¥330 per item. Located roughly 4 minutes walk from Koshigaya Station (or 2 minutes from the 1号店), the 2号店 occupies the 2nd floor of a white building near Arco's delivery entrance. Interior amenities match the 1号店: lockers, coat racks, hand-washing stations, WiFi, and free toys for interactive play. Children are welcomed with guardian accompaniment. The "Mogmog Time" feeding event runs at 16:00 daily when visitors can watch—and sometimes help—with the cats' meals. Capacity limits to 12 people; ticket system operates during peak hours. Parking is not available on-site, though nearby coin lots and Arco parking (with multi-store purchase discounts) serve the area. The 2号店 remains the ideal choice for those preferring a calmer, more intimate experience with especially socialized rescue cats.